Research Article
Relation of Mitral Annulus and Left Atrial Dysfunction to the Severity of Functional Mitral Regurgitation in Patients with Dilated Cardiomyopathy
Table 5
Comparison between patients with trivial/mild, moderate, and severe FMR.
| | Parameters | Trivial/mild FMR (N = 17) | Moderate FMR (N = 25) | Severe FMR (N = 14) | One-way ANOVA between MR severity groups | P (mild vs. moderate FMR) | P (moderate vs. severe FMR) |
| | Indexed LVEDV (ml/m2) | 102 ± 24 | 121 ± 31 | 130 ± 28 | 0.002 | <0.05 | 0.80 | | Indexed LVESV (ml/m2) | 65 ± 21 | 88 ± 30 | 90 ± 17 | 0.07 | 0.10 | 0.36 | | LVEF (%) | 37 ± 10 | 28 ± 10 | 29 ± 9 | 0.02 | <0.01 | 0.69 | | Indexed LAVmax (ml/m2) | 38 ± 12.5 | 45 ± 16 | 59 ± 12 | 0.006 | 0.15 | <0.05 | | Total LAEF (%) | 40 ± 18 | 29 ± 14 | 23 ± 13 | 0.02 | <0.05 | 0.20 | | True LAEF (%) | 20 ± 10 | 18 ± 10 | 13 ± 9 | 0.22 | 0.64 | 0.13 | | MA AP diameter (cm) | 3.1 ± 0.4 | 3.4 ± 0.4 | 3.9 ± 0.5 | <0.001 | <0.05 | <0.001 | | MA ALPM diameter (cm) | 4.1 ± 0.5 | 4.4 ± 0.46 | 4.6 ± 0.5 | 0.007 | <0.05 | 0.15 | | MA circumference (cm) | 11.8 ± 1.4 | 13.0 ± 2.2 | 14.0 ± 1.6 | <0.001 | <0.01 | <0.05 | | MA area 3D (cm2) | 10.4 ± 2.5 | 12.4 ± 2.3 | 14.8 ± 3.4 | <0.001 | <0.05 | <0.01 | | MA area fractional change (%) | 18.6 ± 5.3 | 14 ± 4.3 | 10.6 ± 3.0 | <0.001 | <0.01 | <0.05 | | MA AP diameter change (%) | 11.6 ± 5.7 | 10 ± 5.7 | 8.0 ± 6 | 0.22 | 0.37 | 0.14 | | MA ALPM diameter change (%) | 9.6 ± 4.5 | 7.3 ± 4.0 | 5.4 ± 2.8 | 0.02 | 0.08 | 0.29 | | MA displacement (mm) | 6.3 ± 2.6 | 3.9 ± 2.1 | 4.6 ± 3.8 | 0.03 | <0.01 | 0.44 |
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AP: anteroposterior; ALPM: anterolateral-posteromedial; LAEF: left atrium emptying fraction; LAVmax: left atrium maximal volume; LVEDV: left ventricle end-diastolic volume; LVESV: left ventricular end-systolic volume; LVEF: left ventricular ejection fraction; MA: mitral annulus.
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