Research Article

Correlation between the Serum Platelet-Derived Growth Factor, Angiopoietin-1, and Severity of Coronary Heart Disease

Table 1

Baseline characteristics of all the study subjects.

VariablesControl (n = 29)ACS groups
Total (n = 81)UAP groups (n = 20)AMI groups (n = 61)

Age (years)59.62 ± 9.5960.84 ± 0.7862.2 ± 8.4660.39 ± 11.46
Female, [n (%)]16 (55.17%)64 (79.01%)14 (70.00%)50 (81.96%)
Hypertension, [n (%)]20 (68.97%)49 (60.49%)9 (45%)40 (65.57%)
Diabetes, [n (%)]11 (37.93%)14 (17.28%)4 (20%)10 (16.39%)
Smoking, [n (%)]4 (13.79%)40 (49.38%)6 (30%)34 (55.74%)
BMI (kg/m3)23.56 ± 2.6924.86 ± 3.1423.37 ± 2.5725.34 ± 3.17

History of medication
Nitrates, [n (%)]13 (44.83)47 (58.02)16 (80.0)31 (50.82)
Beta blockers, [n (%)]10 (34.45)41 (50.62)9 (45.0)32 (52.46)
ACEIs/ARBs, [n (%)]12 (41.38)33 (40.74)7 (35.0)26 (42.62)
CCBs, [n (%)]9 (31.03)12 (14.81)5 (25.0)7 (11.47)
Aspirin, [n (%)]29 (100)81 (100)20 (100)61 (100)
Clopidogrel, [n (%)]16 (55.17)80 (98.77)20 (100)60 (98.36)
SBP (mmHg)133.45 ± 15.68128.64 ± 20.52133.85 ± 17.71126.93 ± 21.22
DBP (mmHg)80.03 ± 7.6278.42 ± 12.4978.55 ± 9.0878.38 ± 13.49
FBS (mmol/l)5.58 ± 1.306.83 ± 2.605.87 ± 2.127.15 ± 2.68
HbA1c (%)6.58 ± 1.456.65 ± 2.166.01 ± 0.816.86 ± 2.42
TC (mmol/l)4.57 ± 1.074.97 ± 1.334.43 ± 1.174.52 ± 1.22
LDL-C (mmol/l)2.71 ± 0.772.88 ± 0.942.61 ± 0.762.97 ± 0.98
HDL-C (mmol/l)1.21 ± 0.271.08 ± 0.651.12 ± 0.341.06 ± 0.33
TG (mmol/l)1.78 ± 1.031.69 ± 0.1.221.46 ± 0.711.76 ± 1.35
SUA (μmol/l)319.87 ± 80.32318.82 ± 83.18356.33 ± 84.69338.47 ± 99.07
Scr (μmol/l)74.32 ± 17.7876.78 ± 20.4872.47 ± 17.8778.19 ± 21.21
eGFR92.28 ± 22.1196.26 ± 24.5998.91 ± 23.9995.39 ± 24.91
PLT188.89 ± 52.67186.15 ± 62.85198.9 ± 59.95181.97 ± 63.69

, control vs. other groups; , UAP groups vs. other groups. Data are given as mean ± SD, number (%). ACS, acute coronary syndrome; UAP, unstable angina pectoris; AMI, acute myocardial infarction; BMI, body mass index; ACEIs, angiotensin-converting enzyme inhibitors; ARBs, angiotensin receptor blockers; CCBs, calcium channel blockers; SBP, systolic blood pressure; DBP, diastolic blood pressure; FBS, fasting blood glucose; HbA1c, glycosylated haemoglobin; TC, total cholesterol; LDL-C, low-density lipoprotein cholesterol; HDL-C, high-density lipoprotein cholesterol; TG, triglyceride; SUA, serum uric acid; Scr, serum creatinine; eGFR, estimated glomerular filtration rate; PLT, platelet count.