Prognostic Significance of Chronic Kidney Disease (CKD-EPI Equation) and Anemia in Patients with Chronic Heart Failure Secondary to Chagas Cardiomyopathy
Table 3
Cox proportional hazard model analysis for independent predictors of all-cause mortality.
Univariate
Multivariate
All patients
HR
95% CI
value
HR
95% CI
value
Age (years)
1.00
0.99–1.01
0.876
Gender (male)
1.27
0.88–1.84
0.207
NYHA I functional class
0.54
0.37–0.77
0.001
Heart rate (beats/min)
1.01
1.00–1.02
0.056
SBP (mmHg)
0.98
0.97–1.00
0.006
0.99
0.98–1.00
0.015
DBP (mmHg)
0.98
0.96–1.00
0.015
ICD
0.60
0.34–1.04
0.068
0.48
0.27–0.85
0.012
LAFB
1.63
1.16–2.28
0.005
1.52
1.08–2.13
0.017
LVDD (mm)
1.05
1.03–1.07
<0.001
1.04
1.02–1.06
<0.001
Serum sodium level (mEq/L)
0.93
0.89–0.96
<0.001
0.95
0.92–0.99
0.020
Anemia status
1.31
0.86–2.00
0.207
CKD status
1.21
0.86–1.70
0.271
HR: hazard ratio; CI: confidence interval; NYHA: New York Heart Association Functional Class; SBP: systolic blood pressure; DBP: diastolic blood pressure; ICD: implantable cardioverter-defibrillator; LAFB: left anterior fascicular block; LVDD: left ventricular end-diastolic diameter; CKD: chronic kidney disease.
