Extracellular Matrix Remodeling Factors as Markers of Carotid Artery Atherosclerosis
Table 3
Multiple-factor binary logistic regression analysis of an influence of chosen independent variables including plasma level of OPG, pFN, proMMP-2, and proMMP-9 as predictors of the risk of endarterectomy.
Independent variables
B
S.E.
Wald
Odds ratio
OPG
3.47248
1.30591
7.0706
0.0078
32.2166
Hypertension
3.67218
1.15123
10.1747
0.0014
39.3375
Sex (male)
0.20183
1.00707
0.04017
0.8412
1.2236
Smoking (current)
1.75103
1.17237
2.2308
0.1353
5.7605
pFN
-0.0063167
0.0036775
2.9504
0.0859
0.9937
Hypertension
3.55459
1.21174
8.6051
0.0034
34.9736
Sex (male)
1.05097
1.10861
0.8987
0.3431
2.8604
Smoking (current)
2.83889
1.31857
4.6355
0.0313
17.0968
proMMP-2
5.66930
3.41510
2.7558
0.0969
289.8325
Hypertension
2.65427
1.24455
4.5485
0.0329
14.2147
Sex (male)
0.15236
1.20924
0.01587
0.8997
1.1646
Smoking (current)
3.02960
1.76443
2.9482
0.0860
20.6890
WBC
1.18472
0.39212
9.1284
0.0025
3.2698
proMMP-9
0.41722
2.60737
0.02561
0.8729
1.5177
Hypertension
3.16472
1.15277
7.5368
0.0060
23.6821
Sex (male)
0.79772
1.15184
0.4796
0.4886
2.2205
Smoking (current)
2.40338
1.54465
2.4210
0.1197
11.0605
WBC
0.93230
0.33800
7.6080
0.0058
2.5403
# was considered statistically significant. B: regression coefficient; S.E.: standard error; OPG: osteoprotegerin; pFN: plasma fibronectin; proMMP-2: matrix metalloproteinase 2 proenzyme; proMMP-9: matrix metalloproteinase 9 proenzyme; and WBC: white blood cells.
