Impact of Platelet Glycoprotein Ia/IIa C807T Gene Polymorphisms on Coronary Artery Aneurysms of KD Patients

Table 3

Genotype frequency distribution of platelet glycoprotein Ia/IIa C807T (rs1126643) polymorphism in Kawasaki disease cases and healthy controls.

Genotype	KD cases (n = 818)	Controls (n = 1401)	value^a	OR (95% CI)	value	Adjusted OR (95% CI)	Adjusted value^b
rs1126643	HWE = 0.9626
CC	429 (52.44%)	695 (49.61%)	—	1.00	—	1.00	—
CT	342 (41.81%)	583 (41.61%)	—	0.95 (0.79–1.14)	0.5787	0.95 (0.79–1.14)	0.5784
TT	47 (5.75%)	123 (8.78%)	—	0.62 (0.43–0.89)	0.0085	0.62 (0.43–0.88)	0.0078
Additive	—	—	0.0260	0.86 (0.75–0.99)	0.0347	0.86 (0.75–0.99)	0.0331
Dominant	389 (47.56%)	706 (50.39%)	0.1970	0.89 (0.75–1.06)	0.1972	0.89 (0.75–1.06)	0.1941
Recessive	771 (94.25%)	1278 (91.22%)	0.0082	0.63 (0.45–0.90)	0.0101	0.63 (0.44–0.89)	0.0093
C	1200 (73.35%)	1973 (70.41%)	0.0361	1.00	—	1.00	—
T	436 (26.65%)	829 (29.59%)	—	0.87 (0.76–0.99)	0.0367	0.86 (0.75–0.99)	0.0351

^aTwo-sided χ² test for distributions between Kawasaki disease patients and healthy controls. ^bAdjusted for age and sex status in logistic regression models. OR: odds ratio; CI: confidence interval; KD: Kawasaki disease.