Impact of Platelet Glycoprotein Ia/IIa C807T Gene Polymorphisms on Coronary Artery Aneurysms of KD Patients
Table 4
Stratification analysis of platelet glycoprotein Ia/IIa C807T(rs1126643) gene polymorphism in Kawasaki disease cases and healthy controls.
Variable
rs1126643(cases/controls)
valuea
OR (95% CI)
value
Adjusted OR (95% CI)
Adjusted valueb
CC/CT
TT
Age (months)
≤60
688/1167
41/109
0.0148
0.64 (0.44–0.93)
0.0177
0.64 (0.44–0.93)
0.0176
>60
83/111
6/14
0.2613
0.57 (0.21–1.56)
0.2744
0.57 (0.21–1.55)
0.2719
Gender
Male
516/853
36/78
0.1898
0.76 (0.51–1.15)
0.1957
0.76 (0.51–1.15)
0.1907
Female
255/425
11/45
0.0052
0.41 (0.21–0.80)
0.0094
0.40 (0.20–0.79)
0.0085
Coronary artery outcomes
NCAAs
660/1278
42/123
0.0216
0.66 (0.46–0.95)
0.0254
0.66 (0.46–0.95)
0.0242
CAAs
111/1278
5/123
0.0701
0.47 (0.19–1.17)
0.1039
0.46 (0.18–1.15)
0.0973
a Two-sided χ2 test for distributions between Kawasaki disease patients and healthy controls. bAdjusted for age and sex status in logistic regression models. NCAAs: noncoronary artery aneurysms; CAAs: coronary artery aneurysms; OR: odds ratio; CI: confidence interval; KD: Kawasaki disease.