Research Article

Genotype Variations and Association between PAI-1 Promoter Region (4G/5G and -844G/A) and Susceptibility to Acute Myocardial Infarction and Chronic Stable Angina

Table 1

Clinical characteristics of patients and controls.

CharacteristicGroup I (AMI) (n = 100)Group II (CSA) (n = 100)Group III (control) (n = 100) value

Age (years)55.99 ± 10.3356.38 ± 10.5552.07 ± 14.44

Gender %0.947
 Male828280
 Female181820

Hypertension %544900.572
Diabetes %243700.065
Smoker %364111<0.05
Alcoholic %26267<0.05

Food habits %0.029
Vegetarian395357
Nonvegetarian614743

Family history %212300.865
Total cholesterol(mg/dl)168.1 ± 4.02169.59 ± 3.80163.9 ± 3.980.836
Total HDL(mg/dl)30.18 ± 2.6130.55 ± 2.7441.31 ± 2.590.826
Total LDL(mg/dl)109.49 ± 4.78109.84 ± 5.1999.96 ± 3.22<0.005
BMI23.60 ± 3.5323.97 ± 3.9722.39 ± 3.910.452
PAI-1 antigen (ng/ml)28.62 ± 8.5730.04 ± 8.3222.93 ± 7.220.199

Data presented as mean ± SD except gender, hypertension, diabetes, smoker, alcoholic, food habits, and family history. Significant at . BMI: body mass index; HDL: high density lipoprotein; LDL: low density lipoprotein; PAI: plasminogen activator inhibitor-1.