Genotype Variations and Association between PAI-1 Promoter Region (4G/5G and -844G/A) and Susceptibility to Acute Myocardial Infarction and Chronic Stable Angina
Table 1
Clinical characteristics of patients and controls.
Characteristic
Group I (AMI) (n = 100)
Group II (CSA) (n = 100)
Group III (control) (n = 100)
value
Age (years)
55.99 ± 10.33
56.38 ± 10.55
52.07 ± 14.44
Gender %
0.947
Male
82
82
80
Female
18
18
20
Hypertension %
54
49
0
0.572
Diabetes %
24
37
0
0.065
Smoker %
36
41
11
<0.05
Alcoholic %
26
26
7
<0.05
Food habits %
0.029
Vegetarian
39
53
57
Nonvegetarian
61
47
43
Family history %
21
23
0
0.865
Total cholesterol(mg/dl)
168.1 ± 4.02
169.59 ± 3.80
163.9 ± 3.98
0.836
Total HDL(mg/dl)
30.18 ± 2.61
30.55 ± 2.74
41.31 ± 2.59
0.826
Total LDL(mg/dl)
109.49 ± 4.78
109.84 ± 5.19
99.96 ± 3.22
<0.005
BMI
23.60 ± 3.53
23.97 ± 3.97
22.39 ± 3.91
0.452
PAI-1 antigen (ng/ml)
28.62 ± 8.57
30.04 ± 8.32
22.93 ± 7.22
0.199
Data presented as mean ± SD except gender, hypertension, diabetes, smoker, alcoholic, food habits, and family history. Significant at . BMI: body mass index; HDL: high density lipoprotein; LDL: low density lipoprotein; PAI: plasminogen activator inhibitor-1.