Cardiology Research and Practice / 2021 / Article / Tab 2

Research Article

Platelet Reactivity and Response to Aspirin and Clopidogrel in Patients with Platelet Count Disorders

Table 2

Platelet reactivity presented as a median and 25%–75% interquartile range, IQR.

Aggregation agonistAggregation in patients with thrombocytopeniaAggregation in patients with thrombocythemiaAggregation in controlsStatistical significance
(1)(2)(3)

AA whole group (n = 174)19 (7–28)80 (79–118)23 (15–38)(2) vs. (1)

(2) vs. (3)
AA on ASA only (n = 119)14 (5–29)80 (79–118)23 (17–38)(2) vs. (1)

(2) vs. (3)
AA on DAPT only (n = 55)19 (7–26)80 (70–110)20 (15–31)(2) vs. (1)

(2) vs. (3)
ADP whole group (n = 174)32 (16–44)124 (89–139)50 (32–71)(2) vs. (1)

(2) vs. (3)
ADP on ASA only (n = 119)36 (10–65)136 (89–139)52 (41–73)(2) vs. (1)

(2) vs. (3)
ADP on DAPT only (n = 55)30 (18–41)119 (114–124)36 (21–67)(2) vs. (1)

(2) vs. (3)
TRAP whole group (n = 174)41 (34–60)137 (120–180)90 (70–104)(1) vs. (2)

(2) vs. (3)

(1) vs. (3)
TRAP on ASA only (n = 119)36 (15–72)137 (125–180)86 (71–105)(1) vs. (2)

(2) vs. (3)

(1) vs. (3)
TRAP on DAPT only (n = 55)42 (39–53)129 (104–139)93 (65–103)(1) vs. (2)

(2) vs. (3)

(1) vs. (3)

AU: arbitrary units, AA: arachidonic acid, ADP: adenosine diphosphate, TRAP: thrombin receptor-activating peptide, ASA–acetylsalicylic acid, DAPT: dual antiplatelet therapy, and IQR: 25%–75% interquartile range.