Exercise Improves Endothelial Function via the lncRNA MALAT1/miR-320a Axis in Obese Children and Adolescents

Figure 1

Relative expression of MALAT1 and miR-320a in obese children and adolescents before and after intervention. (a) There was no difference in MALAT1 expression between the matched group and the exercise group, but 12-week exercise training in the exercise group significantly reduced the expression of MALAT1 compared to the matched group receiving only dietary control. (b) After exercise training, the expression of MALAT1 was decreased in obese children and adolescents. (c) There was no difference in miR-320a expression between the matched group and the exercise group, but 12-week exercise training in the exercise group significantly increased the expression of miR-320a compared to the matched group receiving only dietary control. (d) After the exercise training, the expression of miR-320a was elevated in obese children and adolescents. ns, no significance; .

(a)

(b)

(c)

(d)