Clinical Study

Clinical Use of Ultrasensitive Cardiac Troponin I Assay in Intermediate- and High-Risk Surgery Patients

Table 1

Baseline characteristics of all patients, stratified by the occurrence of 30-day cardiovascular events.

All patients (142) Cardiovascular events
Yes ( )No ( )

Men69 (48.6)7 (43.8)62 (49.2)0.79
Age, years 0.80
ASA scoring system0.47
 Class II52 (36.6)4 (25)48 (38.1)
 Class III85 (59.9)12 (75)73 (57.9)
 Class IV5 (3.5)05 (4)
Specific Activity Scale*0.002
 Class I48 (33.8)4 (25)44 (34.9)
 Class II40 (28.2)2 (12.5)38 (30.2)
 Class III32 (22.5)2 (12.5)30 (23.8)
 Class IV13 (9.2)6 (37.5)7 (5.5)
Revised Cardiac Risk Index0.29
 Class II13 (9.2)1 (6.3)12 (9.5)
 Class III84 (59.2)8 (50)76 (60.3)
 Class IV45 (31.7)7 (43.8)38 (30.2)
 Smoking33 (23.2)4 (25)29 (23)0.89
 Hypertension122 (85.9)14 (87.5)108 (85.7)1.00
 Diabetes mellitus58 (40.8)7 (43.8)51 (40.5)0.79
 Atrial fibrillation13 (9.2)2 (12.5)11 (8.7)0.64
 History of congestive heart failure25 (17.6)5 (31.3)20 (15.9)0.16
 Left ventricular ejection fraction (%)** 0.20
 History of myocardial infarction48 (33.8)6 (37.5)42 (33.3)0.78
 Previous percutaneous coronary intervention23 (16.2)6 (37.5)17 (13.5)0.025
 Previous coronary artery bypass graft16 (11.3)3 (18.8)13 (10.3)0.39
 History of cerebrovascular disease47 (33.1)6 (37.5)41 (32.5)0.78
 Renal impairment***35 (24.6)5 (31.3)30 (23.8)0.54
 Peripheral artery disease30 (21.1)9 (56.3)21 (16.7)0.001
Preoperative laboratory tests
 Hemoglobin, mg/dL 0.43
 Serum creatinine, mg/dL1.12 0.87–1.74 1.48 1.07–2.9 1.09 0.86–1.70 0.23
 Creatinine clearance, mL/min 0.53
 NT-proBNP, pg/mL329.3 117.4–1730 1336 181–10175 288 107–1303 0.038
Preoperative medication
 Aspirin65 (45.8)8 (50)57 (45.2)0.79
 Clopidogrel11 (7.7)1 (6.3)10 (7.9)0.39
 Insulin31 (21.8)6 (37.5)25 (19.8)0.12
 Statins75 (52.8)8 (50)67 (53.2)1.00
β-Blockers72 (50.7)11 (68.8)61 (48.4)0.18
 ACE inhibitors85 (59.9)10 (62.5)75 (59.5)1.00

Data are expressed as number (percentage), mean ± SD, or median interquartile range as appropriate. value indicates differences between patients with and without primary cardiovascular events. ASA: American Society of Anesthesiologists; NT-proBNP: N-terminal pro-B-type natriuretic peptide; ACE: angiotensin-converting enzyme.
, ; serum creatinine 2 mg/dL or renal replacement therapy.