Clinical Study

Investigation of Associations between Obesity and LEP G2548A and LEPR 668A/G Polymorphisms in a Turkish Population

Table 4

The distribution of combined genotypes LEP and LEPR gene polymorphism between patients and control groups.

Combined genotypesPatients ( : 127) (%)Controls ( : 105) (%)

AA-AA17 (13.39)19 (18.10)
AA-GA15 (11.81)10 (9.52)
AA-GG5 (3.94)3 (2.86)
GA-AA23 (18.11)22 (20.95)
GA-GA27 (21.26)24 (22.86)
GA-GG11 (8.66)6 (5.71)
GG-AA10 (7.87)9 (8.57)
GG-GA14 (11.02)12 (11.43)
GG-GG5 (3.94)00.047 *

Patients
BMI > 35 kg/m2 ( : 65) (%)30 kg/m2 < BMI ( : 62) (%) < 35 kg/m2

AA-AA8 (12.31)9 (14.52)
AA-GA6 (9.23)9 (14.52)
AA-GG3 (4.62) 2 (3.23)
GA-AA13 (20.00)10 (16.13)
GA-GA11 (16.92)16 (25.81)
GA-GG5 (7.69)6 (9.68)
GG-AA6 (9.23)4 (6.45)
GG-GA9 (13.85)5 (8.06)
GG-GG4 (6.15)1 (1.61)0.37

 *The results that are statistically significant.