Brain Hypothermic Therapy Dramatically Decreases Elevated Blood Concentrations of High Mobility Group Box 1 in Neonates with Hypoxic-Ischemic Encephalopathy

Table 1

Clinical manifestation in cases with and without BHT.

	BHT (−) 𝑛=5	BHT (+) 𝑛=8	𝑃
Gestational age (weeks)	35.8±4.9	40.2±1.2	0.02
Birth weight (g)	2235±953	2716±391	NS
Ap-Sc (1′)	4±1	3±1	NS
Ap-Sc (5′)	8±1	5±1	0.006
UA-pH	7.16±0.12	7.03±0.17	NS
UA-base excess (mmol/L)	−14.8±4.9	−14.2±7.9	NS
UA-lactate (mg/dL)	76.2±31.6	89.0±47.2	NS

Data are means ± standard deviation.
Ap-Sc: Apgar score; UA: umbilical artery; BHT: brain hypothermic therapy.