Are Breast Cancer Molecular Classes Predictive of Survival in Patients with Long Follow-Up?

Table 4

Metastasis sites and local recurrence in accordance with BC molecular subtypes.

Intrinsic subtypes (n)	Local; n (%)	Bone; n (%)	Liver; n (%)	Lung and pleura; n (%)	Brain; n (%)	Endocrine^a; n (%)	Distant LN^b; n (%)	Other^c; n (%)
Luminal A (140)	22 (16)	23 (16)	28 (21)	25 (18)	2 (1)	4 (3)	4 (3)	5 (4)
Luminal B (102)	13 (13)	29 (28)	27 (26)	20 (20)	8 (8)	4 (4)	2 (2)	6 (6)
HER2 positive (24)	7 (29)	3 (12)	7 (29)	6 (25)	4 (17)	1 (4)	1 (4)	1 (4)
TN (38)	5 (13)	12 (32)	13 (34)	14 (37)	4 (11)	1 (3)	1 (3)	1 (3)

aEndocrine sites include thyroid, ovary, and kidney. ^bDistant lymph nodes are considered the nodes that do not belong to the axilla, including the supraclavicular lymph nodes. ^cOther sites comprise peritoneum and pericardium.