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Disease Markers
Volume 35 (2013), Issue 5, Pages 525–529
Research Article

Hypovitaminosis D in Geriatric Acute Care Unit: A Biomarker of Longer Length of Stay

1Department of Geriatrics, Hospital of Laval, 53000 Laval, France
2Division of Geriatric Medicine, Department of Neuroscience, Angers University Hospital, 49933 Angers Cedex 9, France
3Department of Geriatrics, Hospital of Château-Gontier, 53200 Château-Gontier, France
4UPRES EA 4638, Angers University, UNAM, 49000 Angers, France
5Department of Medical Biophysics, Schulich School of Medicine and Dentistry, Robarts Research Institute, The University of Western Ontario, London, ON, Canada N6A 5K8

Received 9 June 2013; Revised 4 September 2013; Accepted 6 September 2013

Academic Editor: Paul Ashwood

Copyright © 2013 Lise Hélard et al. This is an open access article distributed under the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.


Background. Hypovitaminosis D is linked to unstable health in older adults. Our objectives were to determine (i) the difference in length of stay (LOS) in geriatric acute care unit between inpatients with and without hypovitaminosis D and (ii) whether there was a linear association between serum 25-hydroxyvitamin D (25OHD) concentration and LOS. Methods. 253 inpatients admitted in 2008 to the geriatric acute care unit of Angers University Hospital, France, (mean age±standard deviation, 86.2 ± 6.0 years; 66.8% female) were included in this historical cohort study. LOS was calculated by subtracting day of admission from day of discharge. Hypovitaminosis D was defined as 25OHD≤50 nmol/L at the time of admission. Age, gender, place of life, functional independence, reason for admission, number of acute diseases and comorbidities, use of vitamin D supplements, and creatinine clearance were used as confounders. Results. Participants with hypovitaminosis D had longer LOS than their counterparts (15.2 ± 8.2 days versus 12.1 ± 7.0 days, ), underlining a mean difference of 3 days. 25OHD concentration inversely correlated ( , ) and was inversely associated with LOS (adjusted [95%CI: −0.14; −0.02], ). Conclusions. We found an inverse linear association between serum 25OHD concentrations and LOS in a geriatric acute care unit. Participants with 25OHD>50 nmol/L were hospitalized on average 3 days less than those with 25OHD≤50 nmol/L.