| miRNA | Target gene | Techniques | Short description | References |
| miR-206 | ESR1 | WB, RT-PCR, LA | miR-206 decreases estrogen receptor (ER)alpha 1 expression and increases expression of hERalpha2. It also causes posttranscriptional regulation of ERalpha in breast cancer. | [98] | ESR1 | WB, RT-PCR, LA | miR-206 directly targets ERalpha in 3′UTR reporter assays. | [115] | MET | LA | Expression of c-Met protein is down regulated by miR-206. miR-206 expression in tumor cells shows delayed growth, and it could function as a potent tumor suppressor in c-Met-overexpressing tumors. | [116] | NOTCH3 | WB, RT-PCR, LA | miR-206 acts as oncogene as well as tumor suppressor gene. It induces apoptotic cell death and blocks antiapoptotic activity by targeting Notch3. | [117] | CyclinD2 | WB, RT-PCR, LA | miR-206 targets two binding sites in the 3′UTR of cyclin D2 mRNA and suppresses cell proliferation and colony formation at G1/S transition. | [102] |
| miR-31 | RHOA | WB, RT-PCR, LA | miR-31 expresses inversely with metastasis in human breast cancer patients via suppression of metastasis promoting genes RhoA. | [103] | FIH | WB, RT-PCR, LA | miR-31 targets FIH, a hypoxia-inducible factor (HIF) regulatory factor, that inhibits the ability of HIF to act as a transcriptional regulator under normoxic conditions. | [118] | ITGA5, RDX, MMP16, fzd3, MPRIP | LA, ImmunoBlot | miR-31 expresses inversely with metastasis in human breast cancer patients via suppression of metastasis-promoting genes Fzd3, ITGA5, MMP16, MPRIP, and RDX. | [103] | SATB2 | WB, RT-PCR, LA | SATB2 increases tumor cell migration and invasion while miR-31 is down regulated. | [104] |
| miR-146 | CXCR4 | LA | miR-146a expression decreases CXCR4 and inhibits proliferation, differentiation, and maturation as well as MK colony formation. | [119] | CCNA2, PA2G4, BRCA1 | M | miR-146a decreases expression of cell cycle related genes. | [120] | IRF-5, STAT1 | WB, LA | miR-146a expression reduces induction of type I IFN in the peripheral blood mononuclear cells (PBMCs). | [109] | FADD | WB, LA | miR-146a expression impairs both activator protein AP-1 activity and interleukin-2 production induced by TCR engagement. | [121] | MCP-2 | ELISA, LA, | miR-146a maintains HIV-mediated chronic inflammation of brain by decreasing the level of MCP2. | [122] | TBP | WB, LA | miR-146a targets TBP in Huntington disease pathogenesis. | [123] | MMP16 | LA | miR-146b increases glioma cell migration and invasion via MMPs. | [124] |
| miR-91 | AIB1 | WB | miR-91 represses translation of AIB1. | [112] | CCND1 | RT-PCR | miR-91 inhibits breast cancer cell proliferation by targeting cyclin D1. | [113] | E2F1 | RT-PCR | miR-91 down regulates the function of E2F1 by inhibiting AIB1. | [112] |
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