Rather than Rs1800796 Polymorphism, Expression of Interleukin-6 Is Associated with Disease Progression of Chronic HBV Infection in a Chinese Han Population
Table 2
Genotype distribution of rs1800796 in different groups.
rs1800796
HC
IT
CHB
IC
LC
HCC
LC versus CHB
HCC versus CHB
HCC versus LC
()
()
()
()
()
()
OR (95% CI)
P
OR (95% CI)
P
OR (95% CI)
P
Genotype, (%)
CC
176 (66.5)
15 (65.2)
194 (66.4)
17 (68.0)
101 (66.0)
90 (60.8)
1.00
1.00
1.00
CG
78 (29.4)
7 (30.4)
87 (29.8)
7 (28.0)
46 (30.1)
51 (34.5)
1.02 (0.66–1.56)
0.944
1.26 (0.83–1.94)
0.282
1.24 (0.76–2.03)
0.381
GG
11 (4.1)
1(4.4)
11 (3.8)
1 (4.0)
6 (3.9)
7 (4.7)
1.05 (0.38–2.92)
0.929
1.37 (0.52–3.66)
0.526
1.31 (0.42–4.04)
0.638
Dominant model
CC
176 (66.5)
15 (65.2)
194 (66.4)
17 (68.0)
101 (66.0)
90 (60.8)
1.00
1.00
1.00
CG + GG
89 (33.5)
8 (34.8)
98 (33.6)
8 (32.0)
52 (34.0)
58 (39.2)
1.02 (0.67–1.54)
0.928
1.28 (0.85–1.92)
0.244
1.25 (0.78–2.00)
0.349
Hardy-Weinberg equilibrium (P)
0.529
0.874
0.749
0.797
0.791
0.947
Note: value obtained using a standard χ 2 test, and not adjusted for confounding factors. OR: odds ratio; CI: confidence interval; HC: healthy control; IT: immune tolerant; IC: inactive carrier; CHB: chronic hepatitis B; LC: liver cirrhosis; HCC: hepatocellular carcinoma.
