Disease Markers / 2013 / Article / Tab 7

Research Article

Impact of IL12B Gene rs 3212227 Polymorphism on Fibrosis, Liver Inflammation, and Response to Treatment in Genotype 4 Egyptian Hepatitis C Patients

Table 7

Influence of IL12B 1188 A/C SNP stratified according to gender parameter on response to antiviral therapy.

GenotypeaSVR ( )NR ( )P value

AAb genotype 0.977
 M29 (39.2%)17 (28.8%)
 F8 (10.8%)14 (23.7%)
ACc genotype
 M22 (29.7%)14 (23.7%)
 F6 (8.1%)10 (17%)
CCd genotype
 M7 (9.5%)2 (3.4%)
 F2 (2.7%)2 (3.4%)

A allele
 M80 (54.1%)48 (40.7%) 0.822
 F22 (14.9%)38 (32.2%)
C allele
 M36 (24.3%)18 (15.2%)
 F10 (6.7%)14 (11.9%)

M: male; F: female; cross tab for distribution of males and females in relation to IL12B genotypes ; cross tab for distribution of AA males and females in relation to response ; cross tab for distribution of AC males and females in relation to response ; cross tab for distribution of CC males and females in relation to response .

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