Investigation of Genetic Polymorphisms Related to the Outcome of Radiotherapy for Prostate Cancer Patients

Table 1

Description of the analysed polymorphisms in ATM, MDM2, and TP53 genes.

Gene name	Genomic location	Exon/intron	Genomic description	Coding description	Protein description	refSNP	Effect
TP53	17p13.1	Intron 3	g.16225delGinsACCTGGAGGGCTGGGG	c.97-54delGinsACCTGGAGGGCTGGGG	p.?	rs17878362	Intronic
		Intron 3	g.16250C>A	c.97-29C>A	p.?	rs17883323	Intronic
		Intron 3	g.16273C>T	c.97-6C>T	p.?	rs35117667	Intronic
		Exon 4	g.16321C>T	c.139C>T	p.P47S	rs1800371	Missense
		Exon 4	g.16397C>G	c.215C>G	p.P72R	rs1042522	Missense
ATM	11q22-q23	Exon 39	g.86904G>A	c.5557G>A	p.D1853N	rs1801516	Missense
MDM2	12q14.3-q15	Intron 1	g.5610T>G	309T>G	p.?	rs2279744	Intronic

Abbreviations: refSNP: reference SNP cluster report.