Comparison of the Diagnostic Accuracy of the <i>MSLN</i> Gene Products, Mesothelin and Megakaryocyte Potentiating Factor, as Biomarkers for Mesothelioma in Pleural Effusions and Serum

<table>Biomarker concentrations in serum:  biomarker concentrations were determined at least in duplicate by ELISA and individual patient values plotted. (a) MPF as determined using N-ERC assay from IBL; (b) MPF as determined using assay from MBL; (c) correlation between MPF concentrations determined by the two different independent assays; (d) correlation between MPF concentrations determined by MBL assays and mesothelin; (e) soluble mesothelin concentrations; and (f) Receiver Operating Characteristic (ROC) curves showing accuracy of serum biomarkers in differentiating all patients with MM (<svg height="11.225" id="M89" style="vertical-align:-0.1638pt" version="1.1" viewbox="0 0 44.400002 11.225" width="44.400002" xmlns="http://www.w3.org/2000/svg" xmlns:xlink="http://www.w3.org/1999/xlink">
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</svg>) from all other cases (<svg height="11.125" id="M90" style="vertical-align:-0.1638pt" version="1.1" viewbox="0 0 44.400002 11.125" width="44.400002" xmlns="http://www.w3.org/2000/svg" xmlns:xlink="http://www.w3.org/1999/xlink">
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</svg>). (Significant difference between indicated cohorts: ns is not significant;  ***<svg height="11.375" id="M91" style="vertical-align:-0.1638pt" version="1.1" viewbox="0 0 75.025002 11.375" width="75.025002" xmlns="http://www.w3.org/2000/svg" xmlns:xlink="http://www.w3.org/1999/xlink">
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Disease Markers

fig2

Figure 2

Figure 2: Comparison of the Diagnostic Accuracy of the <i>MSLN</i> Gene Products, Mesothelin and Megakaryocyte Potentiating Factor, as Biomarkers for Mesothelioma in Pleural Effusions and Serum 

Figure 2 | Comparison of the Diagnostic Accuracy of the MSLN Gene Products, Mesothelin and Megakaryocyte Potentiating Factor, as Biomarkers for Mesothelioma in Pleural Effusions and Serum 