Disease Markers / 2013 / Article / Fig 2

Research Article

Comparison of the Diagnostic Accuracy of the MSLN Gene Products, Mesothelin and Megakaryocyte Potentiating Factor, as Biomarkers for Mesothelioma in Pleural Effusions and Serum

Figure 2

Biomarker concentrations in serum: biomarker concentrations were determined at least in duplicate by ELISA and individual patient values plotted. (a) MPF as determined using N-ERC assay from IBL; (b) MPF as determined using assay from MBL; (c) correlation between MPF concentrations determined by the two different independent assays; (d) correlation between MPF concentrations determined by MBL assays and mesothelin; (e) soluble mesothelin concentrations; and (f) Receiver Operating Characteristic (ROC) curves showing accuracy of serum biomarkers in differentiating all patients with MM ( ) from all other cases ( ). (Significant difference between indicated cohorts: ns is not significant; *** .)

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