Disease Markers / 2013 / Article / Tab 3

Research Article

Comparison of the Diagnostic Accuracy of the MSLN Gene Products, Mesothelin and Megakaryocyte Potentiating Factor, as Biomarkers for Mesothelioma in Pleural Effusions and Serum

Table 3

Patient demographics and serum mesothelin and MPF concentrations in MM patients and controls.

GroupNumber of cases
(females)
Mean age, years
(range)
Serum mesothelin
(nM)a,d
Serum N-ERC (MPF) (ng/mL)a,b,dSerum MPF
(ng/mL)a,c,d

MM66 (5)66 (48–84)
Cancer lung19 (7)72 (58–82)
Cancer other10 (5)73 (50–82)
Asbestos exposed18 (8)61 (37–86)
ARD14 (1)73 (60–82)
PE-benign23 (7)68 (32–86)

exponentiated mean of log transformed data plus/minus standard error of log transformed data *100.
bMPF concentrations determined from Human N-ERC/Mesothelin Assay (IBL).
cMPF concentrations determined from Human MPF Assay (MBL).
dsignificant difference between indicated cohorts and the mesothelioma cohort as a whole ( ) as determined by Student’s -test (** is ; *** is ).

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