Disease Markers / 2013 / Article / Tab 4

Research Article

Comparison of the Diagnostic Accuracy of the MSLN Gene Products, Mesothelin and Megakaryocyte Potentiating Factor, as Biomarkers for Mesothelioma in Pleural Effusions and Serum

Table 4

Patient demographics and serum creatinine, mesothelin, and MPF concentrations in patients with chronic kidney disease (CKD).

CKD stageNumber of cases  
(number of females)
Mean age, years  
(range)
Median eGFRa
(mL/min/1.73 m²) 
(range)
Serum mesothelin 
(nM)b,d
Serum MPF 
(ng/mL)b,c,d

II30 (12)68 (25–95)74 (62–89)
III32 (16)68 (42–91)40 (30–59)
IV30 (12)64 (32–96)22 (16–28)
V29 (13)66 (46–96)12 (3–14)

estimated glomerular filtration rate was calculated using the Modified Diet in Renal Disease (MDRD) Formula [27].
bexponentiated mean of log transformed data plus/minus standard error of log transformed data *100.
cMPF concentrations determined from Human MPF Assay (MBL).
dsignificant difference between indicated cohorts and the Stage II CKD patient group ( ) as determined by Student’s -test (* is ; *** is ).

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