Nuclear Expression of Snail Is an Independent Negative Prognostic Factor in Human Breast Cancer

Table 2

Association between Snail expression and clinicopathological parameters.

Clinicopathologic parameter	Snail positive		Snail negative		𝑃 value
Mean tumor size (mm) ± SD	35.1±20.4		27.9±15.6		<0.0001
Mean age at diagnosis (years) ± SD	63.2±14.9		63.1±13.3		0.9164
	(𝑛)
Tumor stage					<0.0001
pT1	47	15.3	260	84.7
pT2	128	23.5	416	76.5
pT3	20	28.2	51	71.8
pT4	70	57.8	51	42.2
Lymph node involvement					<0.0001
pN0	115	20.7	440	79.3
pN1	103	25.9	295	74.1
pN2	47	54.0	40	46.0
Tumor grade					<0.0001
1	28	11.0	226	89.0
2	59	13.4	380	86.6
3	178	50.9	172	49.1
Estrogen receptor					<0.0001
ER^+	102	13.0	685	87.0
ER^−	163	64.4	90	35.6
HER2					0.1266
HER2^+	59	29.6	140	70.4
HER2^−	206	24.4	638	75.6
Ki67					<0.0001
Ki67^+	229	28.5	574	71.5
Ki67^−	35	15.0	198	85.0