Research Article

Association between −308 G/A TNF-α Polymorphism and Appendicular Skeletal Muscle Mass Index as a Marker of Sarcopenia in Normal Weight Obese Syndrome

Table 3

Blood biochemical parameters and cardiovascular risk factors according to genotype.

ParametersCarrier (−)
. 70
Carrier (+)
. 25
Mean ± SDMean ± SD

FG (mg/dL)91,33 ± 7,3389,88 ± 7,15
FI ( U/mL)7,98 ± 4,648,00 ± 4,35
HOMA-IR3,35 ± 2,053,21 ± 1,70
TC (mg/dL)203,44 ± 41,45192,12 ± 31,96
HDL-chol (mg/dL)65,16 ± 15,6665,82 ± 14,38
LDL-chol (mg/dL)116,18 ± 35,68110,33 ± 32,53
TG (mg/dL)96,12 ± 39,7587,06 ± 33,79
TC/HDL-chol ratio3,25 ± 0,853,03 ± 0,77
LDL/HDL-chol ratio1,74 ± 0,791,71 ± 0,74
Log TG/HDL-chol ratio1,58 ± 0,841,37 ± 0,58
hs-CRP ( g/dL)0,73 ± 1,780,20 ± 0,50*
TNF-α (pg/mL)26,42 ± 15,3320,62 ± 11,66

.
Carrier (−): −308 TNF-α G/G genotype; carrier (+): −308 TNF-α A/G genotype; FG: fasting glucose; FI: fasting insulin; HOMA-IR: homeostasis model of assessment-insulin resistance; TC: total cholesterol; HDL-chol: HDL cholesterol; LDL-chol: LDL cholesterol; TG: triglycerides; hs-CRP: high-sensitivity C-reactive protein.