RNA-Seq Data Mining: Downregulation of NeuroD6 Serves as a Possible Biomarker for Alzheimer’s Disease Brains

Figure 1

KEGG pathway of 470 DEGs downregulated in the frontal cortex of AD identified by RNA-Seq data analysis. Entrez Gene IDs of 470 DEGs downregulated in the frontal cortex of AD identified by RNA-Seq data analysis of SRA060572 were imported into the Functional Annotation tool of DAVID. It extracted the most significant KEGG pathway termed “neuroactive ligand-receptor interaction” (hsa04080) relevant to the set of imported genes. Downregulated genes are colored yellow.