Research Article
RNA-Seq Data Mining: Downregulation of NeuroD6 Serves as a Possible Biomarker for Alzheimer’s Disease Brains
Table 3
The set of 25 DEGs downregulated in the hippocampal CA1 region during progression of AD identified by microarray data analysis of GSE1297 corresponding to RNA-Seq data analysis of SRA060752.
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The set of 131 DEGs downregulated in the hippocampal CA1 region among incipient, moderate, and severe AD and NC groups by one-way ANOVA satisfying value <0.01 and fold change of severe AD versus NC smaller than 0.6 were extracted by microarray data analysis of GSE1297. Among them, the set of 25 genes corresponding to the core set of 522 DEGs identified by RNA-Seq data analysis of SRA060572 are listed with Entrez Gene ID, gene symbol, gene name, fold change, and value. NeuroD6 is italicized. The complete list of 131 DEGs are shown in Supplementary Table 4. |