Serum Clusterin as a Tumor Marker and Prognostic Factor for Patients with Esophageal Cancer

Table 2

Serum clusterin concentrations in ESCC patients and healthy individuals.

Variable	Number	Concentration (μg/mL)	value
ESCC patients	87	412.3 ± 159.4	<0.0001
Healthy individuals	136	288.8 ± 75.1
ESCC patients (excluding smoker)	30	419.4 ± 154.2	<0.0001
Healthy individuals	136	288.8 ± 75.1
ESCC patients (excluding drinker)	45	413.3 ± 141.9	<0.0001
Healthy individuals	136	288.8 ± 75.1
ESCC patients (excluding diabetes patients)	80	416.3 ± 164.1	<0.0001
Healthy individuals	136	288.8 ± 75.1
ESCC patients (excluding cardiovascular diseases patients)	73	406.88 ± 167.7	<0.0001
Healthy individuals	136	288.8 ± 75.1
ESCC patients (excluding all confounders)	17	400.5 ± 176.2	0.0028
Healthy individuals	136	288.8 ± 75.1

ESSC: esophageal squamous cell carcinoma.
The P value describes the difference in serum clusterin concentration between the samples from the ESCC patients and those from the healthy controls. Significance was determined by independent-samples Mann-Whitney test.