Research Article
Immunohistochemical Correlation of Matrix Metalloproteinase-2 and Tissue Inhibitors of Metalloproteinase-2 in Tobacco Associated Epithelial Dysplasia
Table 3
The mean rank of MMP-2 and TIMP-2 in different grades of dysplasia.
| Cells | Markers | Dysplasia | Cases | Mean rank | Chi-square | value* |
| Basal cells | MMP-2 | Normal | 10 | 8.00 | 27.462 | <0.001 | Mild | 10 | 15.40 | Moderate | 10 | 26.30 | Severe | 10 | 32.30 | TIMP-2 | Normal | 10 | 6.00 | 26.125 | <0.001 | Mild | 10 | 19.15 | Moderate | 10 | 26.05 | Severe | 10 | 30.80 |
| Parabasal cells | MMP-2 | Normal | 10 | 9.00 | 22.065 | <0.001 | Mild | 10 | 17.10 | Moderate | 10 | 24.55 | Severe | 10 | 31.35 | TIMP-2 | Normal | 10 | 7.00 | 25.495 | <0.001 | Mild | 10 | 17.50 | Moderate | 10 | 26.70 | Severe | 10 | 30.80 |
| Fibroblasts | MMP-2 | Normal | 10 | 6.00 | 26.599 | <0.001 | Mild | 10 | 19.25 | Moderate | 10 | 25.25 | Severe | 10 | 31.50 | TIMP-2 | Normal | 10 | 6.00 | 26.660 | <0.001 | Mild | 10 | 19.10 | Moderate | 10 | 25.50 | Severe | 10 | 31.40 |
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MMP-2: matrix metalloproteinase-2; TIMP-2: tissue inhibitor of metalloproteinase-2.
*Kruskal-Wallis test.
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