Research Article
Prediabetes Is Associated with HNF-4α P2 Promoter Polymorphism rs1884613: A Case-Control Study in Han Chinese Population and an Updated Meta-Analysis
Table 3
Comparison of minor allele frequency among studies.
| Rs1884613 | Minor allele frequency | value | OR (95% CI) | Ethnicity | Case | Control |
|
American Diabetes Association [12] | 0.21 | 0.16 | 0.01 | 1.34 (1.07–1.66) | Scandinavia |
|
Dupont and Plummer [13] | 0.27 | 0.21 | 0.017 | 1.38 (1.06–1.80) | Ashkenazi Jewish |
|
Silander et al. [15] | 0.171 | 0.172 | 0.98 | 0.99 (0.73–1.33) | Caucasian |
|
Boj et al. [8] | 0.19 | 0.18 | 0.89 | 1.09 (0.75–1.59) | Discordant sibs | 0.12 | 0.17 | 0.25 | 0.67 (0.41–1.12) | Canada | 0.20 | 0.19 | 0.73 | 1.11 (0.89–1.39) | Scandinavia | 0.19 | 0.15 | 0.12 | 1.25 (0.99–1.58) | Sweden | 0.15 | 0.17 | 0.07 | 0.85 (0.73–0.99) | GCI USA | 0.17 | 0.18 | 0.66 | 0.93 (0.79–1.09) | GCI Poland |
|
Winter [7] | 0.482 | 0.469 | 0.71 | 1.05 (0.79–1.39) | Japanese |
|
Love-Gregory et al. [16] | 0.474 | 0.477 | 0.89 | 1.01 (0.88–1.15) | Japanese |
|
Higgins and Thompson [14] | 0.198 | 0.181 | 0.02 | 1.17 (1.03–1.35) | Norwegian |
| The present study | 0.43 | 0.43 | 0.33 | 1.09 (0.82–1.32) | Chinese |
|
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GCI: Genomics Collaborative, Inc.
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