p16^INK4A and p14^ARF Gene Promoter Hypermethylation as Prognostic Biomarker in Oral and Oropharyngeal Squamous Cell Carcinoma: A Review

Table 2

Classification of hypermethylated candidate genes in OSCC according to their potential biomarker application.

Biomarker type	Genes
Diagnostic	CYCA1, EDNRB, KIF1A, RUNX3
Prognostic	p14, p16, MGMT, ECAD, DCC, DAPK1
Predictive	p16, RASSF
Screening	p15, EDNRB