Research Article
Transporter TAP1-637G and Immunoproteasome PSMB9-60H Variants Influence the Risk of Developing Vitiligo in the Saudi Population
Table 2
Allele and genotype frequencies of
TAP1-D637G and
PSMB9-R60H polymorphisms among Saudi patients (
).
| (a) |
| | Allele | Vitiligo patients | Controls | OR | ( value) | 95% CI | | (frequency) | (frequency) |
| | D | 44 (0.26) | 110 (0.64) | 5.2 | 7.0 (<0.0001) | 3.2–8.2 | | G | 128 (0.74) | 62 (0.36) | | R | 100 (0.58) | 124 (0.72) | 1.86 | 2.7 (0.007) | 1.2–2.9 | | H | 72 (0.42) | 48 (0.28) |
|
|
| (b) |
| | Genotype | (%) | (%) | ( value) |
| | TAP1-D637G: | | | | | DD | 0 (00.0) | 24 (27.9) | 16.2 (<0.0001) | | DG | 44 (51.2) | 62 (72.1) | | GG | 42 (48.8) | 0 (00.0) | | (DG + GG) | 86 (100) | 62 (72.1) | | PSMB9-R60H: | | | | | RR | 26 (30.2) | 44 (51.1) | 4.5 (0.03) | | RH | 48 (55.8) | 36 (41.9) | | HH | 12 (14.0) | 6 (7.0) | | (RH + HH) | 60 (69.8) | 42 (48.9) |
|
|
