Transporter TAP1-637G and Immunoproteasome PSMB9-60H Variants Influence the Risk of Developing Vitiligo in the Saudi Population
Table 4
TAP1-D637G and PSMB9-R60H genotype distribution and allelic frequencies for active versus stable vitiligo phenotypes.
Phenotype
Number of cases (%)
TAP1-D637G genotypesa
Alleles
PSMB9-R60H genotypes
Allele
(%)
(frequency)
(%)
(frequency)
DD
DG
GG
D
G
RR
RH
HH
R
H
Active
52 (60.5)
0 (0.0)
33 (63.5)
19 (36.5)
33 (0.32)
71 (0.68)
9 (17.3)
33 (63.5)
10 (19.2)
51 (0.49)
53 (0.51)
Stable
34 (39.5)
0 (0.0)
10 (29.4)
24 (70.6)
10 (0.15)
58 (0.85)
5 (14.7)
24 (70.6)
5 (14.7)
34 (0.50)
34 (0.50)
OR = 0.66, 95% (CI, 0.01–33.9),
OR = 2.70, 95% (CI, 1.2–5.9),
OR = 1.2, 95% (CI, 0.4–4.0),
OR = 1.0, 95% (CI, 0.5–1.8),
,
,
,
,
CI: confidence interval; OR: odds ratio.
aTAP1-D637G genotype differences between progressive and stable vitiligo cases.
b = no significant difference.
c = a significant difference.