Research Article

Transporter TAP1-637G and Immunoproteasome PSMB9-60H Variants Influence the Risk of Developing Vitiligo in the Saudi Population

Table 4

TAP1-D637G and PSMB9-R60H genotype distribution and allelic frequencies for active versus stable vitiligo phenotypes.

PhenotypeNumber of cases (%)TAP1-D637G genotypesaAllelesPSMB9-R60H genotypesAllele
(%) (frequency) (%) (frequency)
DDDGGGDGRRRHHHRH

Active52 (60.5)0 (0.0)33 (63.5)19 (36.5)33 (0.32)71 (0.68)9 (17.3)33 (63.5)10 (19.2)51 (0.49)53 (0.51)
Stable34 (39.5)0 (0.0)10 (29.4)24 (70.6)10 (0.15)58 (0.85)5 (14.7)24 (70.6)5 (14.7)34 (0.50)34 (0.50)

OR = 0.66, 95% (CI, 0.01–33.9), OR = 2.70, 95% (CI, 1.2–5.9), OR = 1.2, 95% (CI, 0.4–4.0), OR = 1.0, 95% (CI, 0.5–1.8),
, , , ,

CI: confidence interval; OR: odds ratio.
aTAP1-D637G genotype differences between progressive and stable vitiligo cases.
b = no significant difference.
c = a significant difference.