Table of Contents Author Guidelines Submit a Manuscript
Disease Markers
Volume 2014 (2014), Article ID 340214, 8 pages
http://dx.doi.org/10.1155/2014/340214
Research Article

Comparative Plasma Protein Profiling of Hemoglobin H Disease

1Department of Clinical Microscopy, Faculty of Allied Health Sciences, Chulalongkorn University, 254 Phayathai Road, Bangkok 10330, Thailand
2Molecular Pathology Laboratory, Institute of Molecular Biosciences, Mahidol University, 25/25 Phuttamonthon 4 Road, Salaya, Nakhon Pathom 73170, Thailand
3Proteomics Research Laboratory, Genome Institute, National Science and Technology Development Agency, 111 Thailand Science Park, Phahonyothin Road, Khlong Nueng, Khlong Luang, Pathum Thani 12120, Thailand
4Thalassemia Research Center, Institute of Molecular Biosciences, Mahidol University, 25/25 Phuttamonthon 4 Road, Salaya, Nakhon Pathom 73170, Thailand

Received 9 April 2014; Accepted 29 May 2014; Published 15 June 2014

Academic Editor: Sheng Pan

Copyright © 2014 Kamonlak Leecharoenkiat et al. This is an open access article distributed under the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.

Linked References

  1. S. Fucharoen and P. Winichagoon, “Thalassemia and abnormal hemoglobin,” International Journal of Hematology, vol. 76, pp. 83–89, 2002. View at Google Scholar · View at Scopus
  2. P. Wasi, S. Pootrakul, P. Pootrakul, P. Pravatmuang, P. Winichagoon, and S. Fucharoen, “Thalassemia in Thailand,” Annals of the New York Academy of Sciences, vol. 344, pp. 352–363, 1980. View at Google Scholar · View at Scopus
  3. G. Fucharoen, S. Fucharoen, C. Wanhakit, and W. Srithong, “Molecular basis of alpha (0)-thalassemia in northeast of Thailand,” The Southeast Asian Journal of Tropical Medicine and Public Health, vol. 26, pp. 249–251, 1995. View at Google Scholar · View at Scopus
  4. S. Fucharoen, “Genotypes and phenotypes of thalassemia: a discussion,” Annals of the New York Academy of Sciences, vol. 1054, pp. 518–521, 2005. View at Publisher · View at Google Scholar · View at Scopus
  5. C. L. Harteveld, W. P. Oosterhuis, C. H. H. Schoenmakers et al., “α-thalassaemia masked by β gene defects and a new polyadenylation site mutation on the α2-globin gene,” European Journal of Haematology, vol. 84, no. 4, pp. 354–358, 2010. View at Publisher · View at Google Scholar · View at Scopus
  6. D. H. K. Chui, “α-thalassemia: Hb H disease and Hb Barts hydrops fetalis,” Annals of the New York Academy of Sciences, vol. 1054, pp. 25–32, 2005. View at Publisher · View at Google Scholar · View at Scopus
  7. L. E. Lie-Injo, H. G. Lie, J. A. Ager, and H. Lehmann, “alpha-thalasaemia as a cause of hydrops foetalis,” British Journal of Haematology, vol. 8, pp. 1–4, 1962. View at Google Scholar · View at Scopus
  8. D. H. K. Chui, S. Fucharoen, and V. Chan, “Hemoglobin H disease: not necessarily a benign disorder,” Blood, vol. 101, no. 3, pp. 791–800, 2003. View at Publisher · View at Google Scholar · View at Scopus
  9. S. Fucharoen and V. Viprakasit, “Hb H disease: clinical course and disease modifiers,” Hematology, vol. 1, pp. 26–34, 2009. View at Google Scholar · View at Scopus
  10. A. O. M. Wilkie, H. C. Zeitlin, R. H. Lindenbaum et al., “Clinical features and molecular analysis of the α thalassemia/mental retardation syndromes. II. Cases without detectable abnormality of the α globin complex,” American Journal of Human Genetics, vol. 46, no. 6, pp. 1127–1140, 1990. View at Google Scholar · View at Scopus
  11. O. Tangvarasittichai, R. Jeenapongsa, C. Sitthiworanan, and T. Sanguansermsri, “Laboratory investigations of Hb Constant Spring,” Clinical and Laboratory Haematology, vol. 27, no. 1, pp. 47–49, 2005. View at Publisher · View at Google Scholar · View at Scopus
  12. V. Viprakasit and V. S. Tanphaichitr, “Compound heterozygosity for α0-thalassemia (–THAI) and Hb constant spring causes severe Hb H disease,” Hemoglobin, vol. 26, no. 2, pp. 155–162, 2002. View at Publisher · View at Google Scholar · View at Scopus
  13. A. Shah, “Thalassemia syndromes,” Indian Journal of Medical Sciences, vol. 58, no. 10, pp. 445–449, 2004. View at Google Scholar · View at Scopus
  14. H. Wajcman, J. Traeger-Synodinos, I. Papassotiriou et al., “Unstable and thalassemic α chain hemoglobin variants: a cause of Hb H disease and thalassemia intermedia,” Hemoglobin, vol. 32, no. 4, pp. 327–349, 2008. View at Publisher · View at Google Scholar · View at Scopus
  15. E. Vichinsky, “Advances in the treatment of alpha-thalassemia,” Blood Reviews, vol. 26, supplement 1, pp. S31–S34, 2012. View at Publisher · View at Google Scholar · View at Scopus
  16. V. Laosombat, V. Viprakasit, T. Chotsampancharoen et al., “Clinical features and molecular analysis in Thai patients with HbH disease,” Annals of Hematology, vol. 88, no. 12, pp. 1185–1192, 2009. View at Publisher · View at Google Scholar · View at Scopus
  17. S. L. Schrier, A. Bunyaratvej, A. Khuhapinant et al., “The unusual pathobiology of hemoglobin constant spring red blood cells,” Blood, vol. 89, no. 5, pp. 1762–1769, 1997. View at Google Scholar · View at Scopus
  18. S. T. Singer, “Variable clinical phenotypes of α-thalassemia syndromes,” TheScientificWorldJournal, vol. 9, pp. 615–625, 2009. View at Publisher · View at Google Scholar · View at Scopus
  19. N. L. Anderson and N. G. Anderson, “The human plasma proteome: history, character, and diagnostic prospects,” Molecular & Cellular Proteomics, vol. 1, no. 11, pp. 845–867, 2002. View at Google Scholar · View at Scopus
  20. S. Fucharoen, G. Fucharoen, and Y. Fukumaki, “Simple non-radioactive method for detecting haemoglobin Constant Spring gene,” The Lancet, vol. 335, no. 8704, p. 1527, 1990. View at Google Scholar · View at Scopus
  21. Y. T. Liu, J. M. Old, K. Miles, C. A. Fisher, D. J. Weatherall, and J. B. Clegg, “Rapid detection of α-thalassaemia deletions and α-globin gene triplication by multiplex polymerase chain reactions,” British Journal of Haematology, vol. 108, no. 2, pp. 295–299, 2000. View at Publisher · View at Google Scholar · View at Scopus
  22. S. Langlois, J. C. Ford, D. Chitayat et al., “Carrier screening for thalassemia and hemoglobinopathies in Canada,” Journal of Obstetrics and Gynaecology Canada, vol. 30, no. 10, pp. 950–971, 2008. View at Google Scholar · View at Scopus
  23. A. Leecharoenkiat, T. Wannatung, P. Lithanatudom et al., “Increased oxidative metabolism is associated with erythroid precursor expansion in β0-thalassaemia/Hb E disease,” Blood Cells, Molecules, and Diseases, vol. 47, no. 3, pp. 143–157, 2011. View at Publisher · View at Google Scholar · View at Scopus
  24. S. Kuakarn, P. SomParn, P. Tangkijvanich, V. Mahachai, V. Thongboonkerd, and N. Hirankarn, “Serum proteins in chronic hepatitis B patients treated with peginterferon alfa-2b,” World Journal of Gastroenterology, vol. 19, no. 31, pp. 5067–5075, 2013. View at Publisher · View at Google Scholar · View at Scopus
  25. J. Yuan, A. Bunyaratvej, S. Fucharoen, C. Fung, E. Shinar, and S. L. Schrier, “The instability of the membrane skeleton in thalassemic red blood cells,” Blood, vol. 86, no. 10, pp. 3945–3950, 1995. View at Google Scholar · View at Scopus
  26. S. Sriiam, A. Leecharoenkiat, P. Lithanatudom et al., “Proteomic analysis of Hemoglobin H-Constant Spring (Hb H-CS) erythroblasts,” Blood Cells, Molecules, and Diseases, vol. 48, no. 2, pp. 77–85, 2012. View at Publisher · View at Google Scholar · View at Scopus
  27. S. Hatairaktham, C. Srisawat, N. Siritanaratkul et al., “Differential plasma proteome profiles of mild versus severe β-thalassemia/Hb e,” Annals of Hematology, vol. 92, no. 3, pp. 365–377, 2013. View at Publisher · View at Google Scholar · View at Scopus
  28. H. Imrie, F. J. I. Fowkes, P. Michon et al., “Haptoglobin levels are associated with haptoglobin genotype and α+-thalassemia in a malaria-endemic area,” American Journal of Tropical Medicine and Hygiene, vol. 74, no. 6, pp. 965–971, 2006. View at Google Scholar · View at Scopus
  29. M. Maioli, G. B. Vigna, G. Tonolo et al., “Plasma lipoprotein composition, apolipoprotein(a) concentration and isoforms in β-thalassemia,” Atherosclerosis, vol. 131, no. 1, pp. 127–133, 1997. View at Publisher · View at Google Scholar · View at Scopus
  30. P. A. Tovo, R. Miniero, C. Barbera, L. Sacchetti, and M. Saitta, “Serum immunoglobulins in homozygous β-thalassemia,” Acta Haematologica, vol. 65, no. 1, pp. 21–25, 1981. View at Google Scholar · View at Scopus
  31. M. J. Nielsen, H. J. Møller, and S. K. Moestrup, “Hemoglobin and heme scavenger receptors,” Antioxidants and Redox Signaling, vol. 12, no. 2, pp. 261–273, 2010. View at Publisher · View at Google Scholar · View at Scopus
  32. P. W. Buehler, B. Abraham, F. Vallelian et al., “Haptoglobin preserves the CD163 hemoglobin scavenger pathway by shielding hemoglobin from peroxidative modification,” Blood, vol. 113, no. 11, pp. 2578–2586, 2009. View at Publisher · View at Google Scholar · View at Scopus
  33. P. Ascenzi, A. Bocedi, P. Visca et al., “Hemoglobin and heme scavenging,” IUBMB Life, vol. 57, no. 11, pp. 749–759, 2005. View at Publisher · View at Google Scholar · View at Scopus
  34. R. Du, I. Winarsih, B. Ho, and J. L. Ding, “Lipid-free apolipoprotein A-I exerts an antioxidative role against cell-free hemoglobin,” American Journal of Clinical and Experimental Immunology, vol. 1, pp. 33–48, 2012. View at Google Scholar