Research Article
The Role of TPA I/D and PAI-1 4G/5G Polymorphisms in Multiple Sclerosis
Table 3
The uncorrected odds ratios (ORs) for combination genotypes of the TPA I/D and PAI 4G/5G polymorphisms in MS patients and controls.
| | Genotype combinations | MS patients
() | Controls
() | OR (95% CI) | |
| | PAI 4G4G/TPA DD | 58 (6.6%) | 71 (8.3%) | 0.78 (0.54–1.1) | 0.167 | | PAI 5G5G/TPA DD | 39 (4.4%) | 38 (4.4%) | 1 (0.63–1.57) | 0.974 | | PAI 4G carrier/TPA DD | 161 (18.2%) | 185 (21.6%) | 0.81 (0.64–1.02) | 0.074 | | PAI 5G5G/TPA I carrier | 144 (16.3%) | 105 (12.3%) | 1.39 (1.06–1.82) | 0.017 |
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