Disease Markers / 2014 / Article / Tab 3

Clinical Study

Neutrophil-to-Lymphocyte Ratio as a Predictor of Response to Peginterferon plus Ribavirin Therapy for Chronic Hepatitis C

Table 3

Comparison of clinical and laboratory characteristics between high and low neutrophil-lymphocyte ratio of chronic hepatitis C patients.

High N-L ratio ≥ 1.42
()
Low N-L ratio < 1.42
()
value

Age (mean ± SD) (yr)53.5 ± 11.855.0 ± 10.40.101
Gender (male/female)169/137147/1490.192
rs12979860 (CC/CT or TT)218/3296/270.600
Cirrhosis (%)53 (17%)38 (13%)0.139
DM (%)61 (20%)42 (14%)0.039
BMI (kg/m2)24.6 ± 4.0 24.9 ± 3.40.299
Log HCV-RNA (IU/mL)5.6 ± 0.95.3 ± 1.00.002
Genotype 1/non-1140/158123/1630.360
WBC (103/μL)6.2 ± 3.25.4 ± 1.5<0.001
Hemoglobin (g/dL)14.1 ± 1.714.1 ± 1.40.846
Platelet (104/μL)17.8 ± 6.117.3 ± 5.70.307

As determined by ROC curve for best cut-off for predicting SVR.
N-L ratio: neutrophil-lymphocyte ratio; DM: diabetes mellitus; BMI: body mass index; RVR: rapid virological response; WBC: white cell count.

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