Genetic Polymorphisms Involved in Folate Metabolism and Maternal Risk for Down Syndrome: A Meta-Analysis

<div>Forest plots showing the association between the<i> MTRR</i> c.66A&gt;G (rs1801394) polymorphism and maternal risk for DS in overall population. GG/AG versus AA (a), GG versus AG/AA (b), AG versus AA (c), and GG versus AA (d) comparisons are illustrated. The squares represent odds ratios (ORs) and lines represent confidence intervals (95% CI). DSM: Down syndrome mothers; CM: control mothers.</div>

Disease Markers

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Figure 2

Figure 2: Genetic Polymorphisms Involved in Folate Metabolism and Maternal Risk for Down Syndrome: A Meta-Analysis 