Clinical Significance of Survivin Expression in Patients with Urothelial Carcinoma

Table 4

Multivariate analysis of DFS and OS of 56 patients with UCB.

Variables	HR	95% CI	P value
Disease-free survival (DFS)
Age (≥65 versus <65 years)	1.7	0.6–4.8	0.29
Tumor stage (MI versus NMI)^a	1.6	0.6–4.4	0.38
Tumor grade (G2-3 versus G1)	1.5	0.5–9.8	0.49
Survivin expression (high versus low)	3.2	0.4–24.5	0.26
Overall survival (OS)
Age (≥65 versus <65 years)	1.8	0.8–17.6	0.08
Tumor stage (MI versus NMI)^a	2.9	0.8–9.9	0.10
Tumor grade (G2-3 versus G1)	2.1	0.6–10.1	0.46
Survivin expression (high versus low)	12.3	1.5–98.4	0.02

aMI: muscle-invasive; NMI: non-muscle-invasive.