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The paper has been retracted upon the authors’ request, as the routine hospital laboratory evaluation protocol used varied from recommended best practice study design. Although this protocol established the fact that GlucoRx Nexus Voice system was clinically accurate, it could not be used to make valid analytical accuracy statements relating to ISO 15197 standards. GlucoRx Nexus meters are now the formulary choice in the area.

Disease Markers
Volume 2014 (2014), Article ID 602586, 8 pages
Research Article

System Accuracy Evaluation of the GlucoRx Nexus Voice TD-4280 Blood Glucose Monitoring System

1Department of Diabetes & Endocrinology, Countess of Chester Hospital NHS Foundation Trust, Chester CH2 1UL, UK
2Department of Clinical Sciences & Nutrition, University of Chester, Chester CH1 4BJ, UK

Received 7 June 2014; Accepted 15 September 2014; Published 13 October 2014

Academic Editor: Vincent Sapin

Copyright © 2014 Muhammad Khan et al. This is an open access article distributed under the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.


Use of blood glucose (BG) meters in the self-monitoring of blood glucose (SMBG) significantly lowers the risk of diabetic complications. With several BG meters now commercially available, the International Organization for Standardization (ISO) ensures that each BG meter conforms to a set degree of accuracy. Although adherence to ISO guidelines is a prerequisite for commercialization in Europe, several BG meters claim to meet the ISO guidelines yet fail to do so on internal validation. We conducted a study to determine whether the accuracy of the GlucoRx Nexus TD-4280 meter, utilized by our department for its cost-effectiveness, complied with ISO guidelines. 105 patients requiring laboratory blood glucose analysis were randomly selected and reference measurements were determined by the UniCel DxC 800 clinical system. Overall the BG meter failed to adhere to the ≥95% accuracy criterion required by both the 15197:2003 (overall accuracy 92.4%) and 15197:2013 protocol (overall accuracy 86.7%). Inaccurate meters have an inherent risk of over- and/or underestimating the true BG concentration, thereby risking patients to incorrect therapeutic interventions. Our study demonstrates the importance of internally validating the accuracy of BG meters to ensure that its accuracy is accepted by standardized guidelines.