Matrix Metalloproteinase-9: Its Interplay with Angiogenic Factors in Inflammatory Bowel Diseases

Table 2

Correlations between MMP-9 and studied factors in Crohn’s disease (CD) and ulcerative colitis (UC).

Factor	CD		UC
	rho	𝑃	rho	𝑃
CRP	0.479	<0.0001*	0.201	0.075
ESR	0.194	0.139	0.394	<0.001*
HGB	−0.204	0.121	−0.209	0.062
IL-1	0.317	0.035*	−0.194	0.139
IL-6	0.532	<0.001*	0.277	0.038*
PLT	0.418	0.002*	0.248	0.026*
TNF-α	−0.0131	0.930	0.0233	0.859
WBC	0.476	<0.001*	0.266	0.018*
Midkine	0.516	<0.001*	0.228	0.037*
VEGF-A	0.377	0.040*	0.072	0.660
PDGF-BB	0.326	0.0408*	0.301	0.032*
CDAI	0.292	0.029*	—	—
CAI			0.342	0.010*

CRP: C-reactive protein; ESR: erythrocyte sedimentation rate; HGB: hemoglobin; IL-1, -6: interleukin-1, -6; PLT: platelet count; TNF-α: tumor necrosis factor α; WBC: white blood cells; VEGF-A: vascular endothelial growth factor A; PDGF-BB: platelet-derived growth factor-BB; CDAI: Crohn’s disease activity index; CAI: clinical activity index. Asterisks indicate statistically significant correlations.