Diagnostic and Prognostic Role of Preoperative Circulating CA 15-3, CA 125, and Beta-2 Microglobulin in Renal Cell Carcinoma

Table 2

Comparisons of the biomarkers median values between RCC with tumor size ≤7 versus >7 cm (a) and between Fuhrman grades 1-2 versus 3-4 (b).

(a)  

	Tumor size				𝑃 value
	≤7 cm		>7 cm
	Median	95% CI	Median	95% CI
CA 15-3 (U/mL)	19.79	18.72–21.20	32.84	28.90–37.10	<0.0001
CA 125 (U/mL)	10.02	9.41–11.31	14.75	10.62–20.77	0.002
β-2 m (mg/L)	1.90	1.80–2.00	2.30	2.10–2.70	<0.0001

(b)  

	Fuhrman grade				𝑃 value
	G1-2		G3-4
	Median	95% CI	Median	95% CI
CA 15-3 (U/mL)	20.06	18.99–21.87	25.39	22.11–27.85	0.0007
CA 125 (U/mL)	9.67	9.16–11.01	13.89	10.49–16.17	0.002
β-2 m (mg/L)	2.00	1.80–2.00	2.31	1.99–2.60	0.001