Research Article
Association of Tagging SNPs in the MTHFR Gene with Risk of Type 2 Diabetes Mellitus and Serum Homocysteine Levels in a Chinese Population
Table 4
Association between MTHFR polymorphisms and serum tHcy levels in health controls.
| SNP | M/m | tHcy (mol/L) | | MM | Mm | mm |
| rs12121543 | C/A | 12.5 (10.1–14.6) | 11.8 (9.7–13.5) | 10.4 (8.5–14.1) | 0.21 | rs13306561 | T/C | 12.1 (9.9–14.4) | 10.5 (8.4–13.7) | 12.3 (10.0–14.4) | 0.87 | rs13306553 | T/C | 12.1 (10.0–14.4) | 12.4 (10.0–14.4) | 9.1 (8.1–11.8) | 0.45 | rs9651118 | T/C | 12.5 (9.8–14.6) | 12.1 (10.1–14.1) | 11.3 (9.3–13.4) | 0.02 | rs1801133 | C/T | 11.3 (9.3–13.7) | 12.8 (10.9–14.4) | 11.9 (9.5–16.6) | 0.0002 | rs2274976 | G/A | 12.1 (9.9–14.4) | 12.3 (10.0–14.1) | 10.7 (8.4–13.7) | 0.84 | rs4846048 | A/G | 12.4 (10.0–14.4) | 11.4 (9.5–13.3) | 10.7 (8.6–20.1) | 0.28 | rs1801131 | A/C | 12.5 (10.1–14.6) | 11.8 (9.7–13.6) | 10.8 (8.6–14.1) | 0.26 | rs17037396 | C/T | 12.1 (9.9–14.2) | 12.1 (10.0–14.6) | 13.7 (12.5–15.2) | 0.67 |
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Adjusted for age, sex, BMI, and hypertension. M indicates major allele; m indicates minor allele.
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