Research Article

Influence of Adiposity-Related Genetic Markers in a Population of Saudi Arabians Where Other Variables Influencing Obesity May Be Reduced

Table 4

Effect size of SNPs used for weighted genetic risk scores.

SNP Nearest geneEffect size

rs10767664BDNF 0.19
rs3751812FTO 0.36*
rs9939609FTO ā€”
rs9941349FTO ā€”
rs10938397GNPDA2 0.18
rs2815752NEGR1 0.13
rs571312MC4R 0.23
rs543874SEC16B 0.22
rs7359397SH2B1 0.15
rs713586RBJ 0.14
rs2867125TMEM18 0.31

rs3751812: effect size taken from NFBC1966 cohort in Finland [11]; all others taken from GIANT consortium genome-wide association meta-analysis [9].