Research Article
First-Line Gemcitabine Plus Cisplatin in Nonsmall Cell Lung Cancer Patients
Table 2
Expression of RRM1, ERCC1, and BRCA1 in the group of different histological types, TMN stages, and response to chemotherapy.
| | Characteristic | RRM1 | ERCC1 | BRCA1 | | Low | High | | Low | High | | Low | High | |
| | Age | | | | | | | | | | | >65 | 5 | 6 | 1.000 | 6 | 5 | 1.000 | 6 | 5 | 1.000 | | <65 | 12 | 11 | 11 | 12 | 11 | 12 | | Smoker | | | | | | | | | | | Yes | 7 | 6 | 1.000 | 8 | 5 | 0.290 | 8 | 5 | 0.290 | | No | 10 | 11 | 9 | 12 | 9 | 12 | Stage
| | | | | | | | | | | IIIB | 4 | 5 | 1.000 | 5 | 4 | 1.000 | 5 | 4 | 1.000 | | IV | 13 | 12 | 13 | 12 | 12 | 13 | | Histology | | | | | | | | | | | Squamous cell carcinoma | 5 | 5 | 1.000 | 3 | 7 | 0.132 | 4 | 6 | 0.708 | | Adenocarcinoma | 12 | 12 | 14 | 10 | 13 | 11 | | Response | | | | | | | | | | | Partial | 9 | 1 | 0.007 | 5 | 5 | 1.000 | 7 | 3 | 0.259 | | Stable/progressive | 8 | 16 | 12 | 12 | 10 | 14 |
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