Research Article
Validation of Serum Biomarkers Derived from Proteomic Analysis for the Early Screening of Preeclampsia
Table 1
Maternal and neonatal characteristics of cases and controls included in the study [
17].
| | | Controls ( = 48) | PE ( = 24) | Statistics |
| | Maternal age (y) | 32.2
28.8–37.3 | 32.9
27.3–35.0 | NS | | Prepregnancy BMI (kg/m2) | 24.8
22.5–26.2 | 27.9
23.4–32.9 | = .000 | | Cigarette smoker | 35 (73%) | 12 (50%) | = .028 | | Nulliparous | 29 (60.4%) | 22 (91.6%) | = .013 | |
Parous | 19 (39.6%) | 2 (8.4%) | | Family history of PE | 0 | 0 | — | | Conception | | | | | Spontaneous | 42 (87.5%) | 24 (100%) | = .090 | | IVF | 6 (12.5%) | 0 | | Medical history | | | | | Diabetes mellitus | 0 | 0 | — | | Thrombophilia | 0 | 1 | | Mode of delivery | | | | | Vaginal birth () | 33 (68.7%) | 8 (33.3%) | = .013 | | Caesarean delivery () | 15 (31.3%) | 16 (66.6%) | | Gestational age at delivery (wk) | 40.2
37.2–42.0 | 38.1
32.1–40.6 | | | <37 wk () | 0 | 7 | = .000 | | <34 wk () | 0 | 2 | | Birth weight (g) | 3410
2880–4250 | 2780
980–3950 | | | >10th percentile () | 48 | 11 | = .020 | | <10th percentile () | 0 | 11 | | <5th percentile () | 0 | 2 |
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