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Research Article

CYP7A1 Gene Polymorphism Located in the 5′ Upstream Region Modifies the Risk of Coronary Artery Disease

Table 4

Distribution of the genotypes and alleles of the rs7833904 polymorphism in the female subgroups of coronary artery disease (CAD) patients and controls.

Genotype/alleleCAD
Control
ModelOR (CI 95%), P
(%) (%)

TT16 (35.56%)17 (22.97%)Additive1
AT32 (32.65%)30 (29.70%)1.70 (0.70–4.11), 0.338
AA14 (24.56%)16 (36.26%)0.93 (0.34–2.50), 0.914
AA + AT
TT
46 (74.19%)
16 (35.56%)
46 (73.01%)
17 (22.97%)
Dominant1.06 (0.47–2.38), 0.881
1
AT + TT
AA
48 (77.41%)
14 (24.56%)
47 (74.60%)
16 (36.26%)
Recessive1.16 (0.51–2.70), 0.712
1

A60 (48.38%)62 (49.20%)1.03 (0.63–1.70), 0.897
T64 (51.62%)64 (50.80%)0.97 (0.58–1.59), 0.897

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