Research Article

CYP7A1 Gene Polymorphism Located in the 5′ Upstream Region Modifies the Risk of Coronary Artery Disease

Table 5

Serum lipid levels and BMI values with respect to genotypes and alleles of the rs7833904 polymorphism in the groups of coronary artery disease (CAD) patients and controls.

Control
Genotype/alleleTC
mmol/L ± SD
LDL-C
mmol/L ± SD
HDL-C
mmol/L ± SD
TG
mmol/L ± SD
BMI
kg/m2 ± SD

AA 4.95 ± 1.022.92 ± 0.921.56 ± 0.611.25 ± 0.6025.40 ± 3.83
AT5.18 ± 1.273.23 ± 1.231.46 ± 0.581.34 ± 0.6125.91 ± 3.82
TT 5.12 ± 1.193.21 ± 1.081.35 ± 0.461.54 ± 0.8026.29 ± 3.43
A5.11 ± 1.203.13 ± 1.701.49 ± 0.591.31 ± 0.6025.76 ± 3.81
T4.95 ± 1.022.92 ± 0.981.56 ± 0.611.25 ± 0.6025.41 ± 3.83

CAD
Genotype/alleleTC
mmol/L ± SD
LDL-C
mmol/L ± SD
HDL-C
mmol/L ± SD
TG
mmol/L ± SD
BMI
kg/m2 ± SD

AA 5.76 ± 1.303.99 ± 1.161.10 ± 0.312.00 ± 1.0527.08 ± 4.22
AT5.80 ± 1.363.97 ± 1.221.13 ± 0.311.97 ± 1.1126.75 ± 4.04
TT 5.94 ± 1.504.20 ± 1.131.12 ± 0.311.80 ± 0.8527.45 ± 3.67
A5.79 ± 1.333.98 ± 1.201.12 ± 0.301.98 ± 1.0826.87 ± 4.10
T5.85 ± 1.424.04 ± 1.271.12 ± 0.301.92 ± 1.0326.98 ± 3.92