Table of Contents Author Guidelines Submit a Manuscript
Disease Markers
Volume 2015 (2015), Article ID 286719, 9 pages
http://dx.doi.org/10.1155/2015/286719
Research Article

Blockade of Aquaporin 1 Inhibits Proliferation, Motility, and Metastatic Potential of Mesothelioma In Vitro but not in an In Vivo Model

1Department of Anatomical Pathology, Flinders University, Adelaide, Bedford, SA 5042, Australia
2SA Pathology, Department of Surgical Pathology, Flinders Medical Centre, Adelaide, Bedford, SA 5042, Australia
3Asbestos Diseases Research Institute, Bernie Banton Centre, NSW 2139, Australia
4School of Medicine, University of Sydney, NSW 2006, Australia

Received 14 December 2014; Accepted 16 February 2015

Academic Editor: Marco E. M. Peluso

Copyright © 2015 Sonja Klebe et al. This is an open access article distributed under the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.

Linked References

  1. G. Gatta, L. Ciccolallo, I. Kunkler et al., “Survival from rare cancer in adults: a population-based study,” The Lancet Oncology, vol. 7, no. 2, pp. 132–140, 2006. View at Publisher · View at Google Scholar · View at Scopus
  2. ADRI OC, Guidelines for the Diagnosis and Treatment of Malignant Pleural Mesothelioma, Asbestos Diseases Research Institute, Rhodes, Greece, 2013.
  3. Australian Institute of Health and Welfare, IHW: Cancer Incidence Projections: Australia 2011 to 2020, Cancer Series, Australian Institute of Health and Welfare, Canberra, Australia, 2012.
  4. B. W. S. Robinson, A. W. Musk, and R. A. Lake, “Malignant mesothelioma,” The Lancet, vol. 366, no. 9483, pp. 397–408, 2005. View at Publisher · View at Google Scholar · View at Scopus
  5. NOHSC, The Incidence of Mesothelioma in Australia 1997 to 1999: Australian Mesothelioma Register Report 2002, National Occupational Health and Safety Commission, Canberra, Australia, 2002.
  6. J. Leigh, P. Davidson, L. Hendrie, and D. Berry, “Malignant mesothelioma in Australia, 1945–2000,” The American Journal of Industrial Medicine, vol. 41, no. 3, pp. 188–201, 2002. View at Publisher · View at Google Scholar · View at Scopus
  7. P. A. Zucali, F. De Vincenzo, M. Simonelli, and A. Santoro, “Future developments in the management of malignant pleural mesothelioma,” Expert Review of Anticancer Therapy, vol. 9, no. 4, pp. 453–467, 2009. View at Publisher · View at Google Scholar · View at Scopus
  8. P. Astoul, E. Roca, F. Galateau-Salle, and A. Scherpereel, “Malignant pleural mesothelioma: from the bench to the bedside,” Respiration, vol. 83, no. 6, pp. 481–493, 2012. View at Publisher · View at Google Scholar · View at Scopus
  9. A. S. Verkman, M. Hara-Chikuma, and M. C. Papadopoulos, “Aquaporins—new players in cancer biology,” Journal of Molecular Medicine (Berlin, Germany), vol. 86, no. 5, pp. 523–529, 2008. View at Publisher · View at Google Scholar · View at Scopus
  10. K. Ishibashi, S. Hara, and S. Kondo, “Aquaporin water channels in mammals,” Clinical and Experimental Nephrology, vol. 13, no. 2, pp. 107–117, 2009. View at Publisher · View at Google Scholar · View at Scopus
  11. L. S. King and P. Agre, “Pathophysiology of the aquaporin water channels,” Annual Review of Physiology, vol. 58, pp. 619–648, 1996. View at Publisher · View at Google Scholar · View at Scopus
  12. A. S. Verkman, “Physiological importance of aquaporin water channels,” Annals of Medicine, vol. 34, no. 3, pp. 192–200, 2002. View at Publisher · View at Google Scholar · View at Scopus
  13. M. Endo, R. K. Jain, B. Witwer, and D. Brown, “Water channel (aquaporin 1) expression and distribution in mammary carcinomas and glioblastomas,” Microvascular Research, vol. 58, no. 2, pp. 89–98, 1999. View at Publisher · View at Google Scholar · View at Scopus
  14. K. Oshio, D. K. Binder, Y. Liang et al., “Expression of the aquaporin-1 water channel in human glial tumors,” Neurosurgery, vol. 56, no. 2, pp. 375–381, 2005. View at Publisher · View at Google Scholar · View at Scopus
  15. M. O. Hoque, J.-C. Soria, J. Woo et al., “Aquaporin 1 is overexpressed in lung cancer and stimulates NIH-3T3 cell proliferation and anchorage-independent growth,” The American Journal of Pathology, vol. 168, no. 4, pp. 1345–1353, 2006. View at Publisher · View at Google Scholar · View at Scopus
  16. C. Clapp and G. M. de la Escalera, “Aquaporin-1: a novel promoter of tumor angiogenesis,” Trends in Endocrinology and Metabolism, vol. 17, no. 1, pp. 1–2, 2006. View at Publisher · View at Google Scholar · View at Scopus
  17. A. S. Verkman, M. Hara-Chikuma, and M. C. Papadopoulos, “Aquaporins—new players in cancer biology,” Journal of Molecular Medicine, vol. 86, no. 5, pp. 523–529, 2008. View at Publisher · View at Google Scholar · View at Scopus
  18. L. S. King, S. Nielsen, and P. Agre, “Aquaporin-1 water channel protein in lung: ontogeny, steroid-induced expression, and distribution in rat,” The Journal of Clinical Investigation, vol. 97, no. 10, pp. 2183–2191, 1996. View at Publisher · View at Google Scholar · View at Scopus
  19. J. Jiang, J. Hu, and C. Bai, “Role of aquaporin and sodium channel in pleural water movement,” Respiratory Physiology & Neurobiology, vol. 139, no. 1, pp. 83–88, 2003. View at Publisher · View at Google Scholar · View at Scopus
  20. Y. Song, B. Yang, M. A. Matthay, T. Ma, and A. S. Verkman, “Role of aquaporin water channels in pleural fluid dynamics,” American Journal of Physiology: Cell Physiology, vol. 279, no. 6, pp. C1744–C1750, 2000. View at Google Scholar · View at Scopus
  21. S. C.-H. Kao, N. Armstrong, B. Condon et al., “Aquaporin 1 is an independent prognostic factor in pleural malignant mesothelioma,” Cancer, vol. 118, no. 11, pp. 2952–2961, 2012. View at Publisher · View at Google Scholar · View at Scopus
  22. G. P. Nicchia, C. Stigliano, A. Sparaneo, A. Rossi, A. Frigeri, and M. Svelto, “Inhibition of aquaporin-1 dependent angiogenesis impairs tumour growth in a mouse model of melanoma,” Journal of Molecular Medicine (Berl), vol. 91, no. 5, pp. 613–623, 2013. View at Publisher · View at Google Scholar · View at Scopus
  23. J. Hu and A. S. Verkman, “Increased migration and metastatic potential of tumor cells expressing aquaporin water channels,” The FASEB Journal, vol. 20, no. 11, pp. 1892–1894, 2006. View at Publisher · View at Google Scholar · View at Scopus
  24. A. S. Verkman, “Applications of aquaporin inhibitors,” Drug News & Perspectives, vol. 14, no. 7, pp. 412–420, 2001. View at Publisher · View at Google Scholar · View at Scopus
  25. A. J. Yool, O. H. Brokl, T. L. Pannabecker, W. H. Dantzler, and W. D. Stamer, “Tetraethylammonium block of water flux in aquaporin-1 channels expressedinkidney thin limbs of Henle`s loop and a kidney-derived cell line,” BMC Physiology, vol. 2, article 1, 2002. View at Publisher · View at Google Scholar · View at Scopus
  26. S. Saadoun, M. C. Papadopoulos, M. Hara-Chikuma, and A. S. Verkman, “Impairment of angiogenesis and cell migration by targeted aquaporin-1 gene disruption,” Nature, vol. 434, no. 7034, pp. 786–792, 2005. View at Publisher · View at Google Scholar · View at Scopus
  27. J. X. Zhang, C. M. Xie, Z. W. Zhu, H. Y. Huang, and Z. L. Zeng, “Potential role of AQP1 and VEGF in the development of malignant pleural effusion in mice,” Medical Oncology, vol. 29, no. 2, pp. 656–662, 2012. View at Publisher · View at Google Scholar
  28. M. C. Papadopoulos, S. Saadoun, and A. S. Verkman, “Aquaporins and cell migration,” Pflugers Archiv, vol. 456, no. 4, pp. 693–700, 2008. View at Publisher · View at Google Scholar · View at Scopus
  29. E. Monzani, R. Bazzotti, C. Perego, and C. A. M. La Porta, “AQP1 is not only a water channel: it contributes to cell migration through Lin7/beta-catenin,” PLoS ONE, vol. 4, no. 7, Article ID e6167, 2009. View at Publisher · View at Google Scholar · View at Scopus
  30. K. Iwahori, S. Serada, M. Fujimoto et al., “Overexpression of SOCS3 exhibits preclinical antitumor activity against malignant pleural mesothelioma.,” International Journal of Cancer, vol. 129, no. 4, pp. 1005–1017, 2011. View at Google Scholar · View at Scopus
  31. A. B. Tsuji, C. Sogawa, A. Sugyo et al., “Comparison of conventional and novel pet tracers for imaging mesothelioma in nude mice with subcutaneous and intrapleural xenografts,” Nuclear Medicine and Biology, vol. 36, no. 4, pp. 379–388, 2009. View at Publisher · View at Google Scholar · View at Scopus
  32. K. Kuribayashi, H. Hirano, K. Nakasho et al., “Cell-adhesion molecule expression and the proliferation of malignant mesothelioma: a post-mortem examination,” Anticancer Research, vol. 34, no. 6, pp. 3061–3065, 2014. View at Google Scholar