Overexpression of FRAT1 Is Associated with Malignant Phenotype and Poor Prognosis in Human Gliomas
Table 1
Measurements of FRAT1 IRS, Pi, Ii, and MVD in gliomas.
Glioma tissues
FRAT1 IRS
Pi %
Ii %
MVD
Grade I
10
1.30 ± 1.77
12.62 ± 11.24
9.18 ± 12.03
30.36 ± 11.69
Grade II
19
2.63 ± 2.91
23.66 ± 13.69
19.84 ± 15.66
51.08 ± 15.27
Grade III
16
4.50 ± 3.76
35.19 ± 16.08
26.80 ± 18.05
73.81 ± 24.52
Grade IV
23
6.70 ± 3.89
48.23 ± 21.05
39.91 ± 19.12
90.14 ± 29.28
Total
68
4.25 ± 3.86a
33.06 ± 20.93a
26.70 ± 19.93a
66.59 ± 31.05a
as compared among Grades I to IV of brain gliomas (by ANOVA). IRS, immunoreactivity score; Pi, proliferative index; Ii, invasive index; MVD, microvessel density.