Postoperative CA19-9 Change Is a Useful Predictor of Intrahepatic Cholangiocarcinoma Survival following Liver Resection
Table 3
Comparison of clinicopathological factors according to recurCA19-9 (recurCA19-9 >37 versus recurCA19-9 ≤37) in patients with elevated preopCA19-9† and normalized postopCA19-9 ().
Factors
RecurCA19-9 ≤37 U/mL ()
RecurCA19-9 >37 U/mL ()
value
Age (>65/≤65 years)
8/2
3/5
0.145
Sex (male/female)
5/5
7/1
0.152
Viral hepatitis B (yes/no)
1/9
0/8
0.556
Tumor size (>5/≤5 cm)
7/3
7/1
0.558
Major vascular invasion (yes/no)
3/7
1/7
0.767
Microvascular invasion (yes/no)
4/6
6/2
0.051
Perineural invasion (yes/no)
4/6
7/1
0.042
Lymphatic invasion (yes/no)
4/6
4/4
0.520
Intrahepatic metastasis (yes/no)
5/5
6/2
0.367
T stage, AJCC 6th (I, II/III, IV)
4/4
13/6
0.352
Lymph node metastasis (yes/no)
5/5
6/2
0.367
Adjuvant therapy (yes/no)
5/5
4/4
1.00
Resection margin (>1/≤1 cm)
9/1
6/2
0.206
Intrahepatic recurrence (yes/no)
7/3
6/2
0.618
Extrahepatic recurrence (yes/no)
2/8
3/5
0.642
Disease-free survival (months)
10
4
0.126
PreopCA19-9†: preoperative CA19-9, postopCA19-9: postoperative lowest CA19-9, and recurCA19-9: CA 19-9 levels at recurrence.
