Serum Survivin Levels and Outcome of Chemotherapy in Patients with Malignant Mesothelioma

Table 2

Survivin levels before chemotherapy and change in survivin levels after chemotherapy and MM treatment outcome.

Treatment outcome	Survivin levels before chemotherapy (pg/mL, median (25% to 75%))		Change in survivin levels (pg/mL, median (25% to 75%))
	All patients ()	Patients exposed to asbestos ()	All patients ()	Patients exposed to asbestos ()
Complete response	0 (0–37.0)	0 (0–37.0)	114.3 (6.0 to 304.5)	114.3 (6.0 to 304.5)
Partial response	33.9 (0–803.4)	4.1 (0–174.8)	61.6 (0 to 163.9)	62.2 (0 to 110.3)
Stable disease	0 (0–124.9)	0 (0–71.9)	0 (−2.0 to 66.9)	0 (−4.1 to 55.3)
Progress	199.7 (38.0–3102.7)	166.9 (62.0–2377.0)	−45.2 (−975.4 to 0)	−88.6 (−1370.9 to −39.8)
Kruskal-Wallis test statistic	7.951	6.561	8.892	14.365
value	0.047	0.087	0.031	0.002

: number of patients.