Research Article
Hypermethylation-Associated Silencing of miR-125a and miR-125b: A Potential Marker in Colorectal Cancer
Table 1
Clinicopathological features of CRC patients and BSP analysis of miR-125a in tumor tissues.
| Variable | Hypermethylation and low expression | Hypermethylation and high expression | Methylation and low expression | Methylation and high expression | value |
| Sex | | | | | 0.686 | Male (46) | 38 | 2 | 1 | 5 | | Female (22) | 17 | 1 | 1 | 3 | | Age (years) | | | | | 0.343 | 50 (16) | 13 | 1 | 0 | 2 | | 50 (52) | 42 | 2 | 2 | 6 | | Histological differentiation | | | | | 1.000 | Good or moderate | 31 | 1 | 1 | 6 | | Poor or none | 24 | 2 | 1 | 2 | | Lymph node metastasis | | | | | 0.686 | Negative | 28 | 1 | 1 | 8 | | Positive | 24 | 2 | 1 | 3 | | Grade | | | | | 0.886 | Low grade (I + II) | 25 | 1 | 1 | 8 | | High grade (III + IV) | 30 | 2 | 1 | 0 | |
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